Cancer tissue-originated spheroid culture for living tissue

Targeting the Wnt receptor complex to treat cancer

Colon myofibroblasts and crypt formation

Cytokine and Wnt signalling in intestinal tumour growth

Consequences of induced senescence in intestinal organoids

Signalling networks in intestinal organoids

Repair of CFTR in intestinal organoids from cystic fibrosis patients

The Central Role of Wnt Signaling and Organoid Technology in Personalizing Anticancer Therapy

Basic Research

Basic Research

Technology

Technology

Challenges and applications of organoid technology

Cell-cell contacts and culture of spheroids

Model systems and potential applications for organoids

Immune responses to tumour-derived organoids

Three dimensional cultures and precision medicine

Organoids: the body builders

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Applications for organoid technology in disease and development

Precision approaches to cancer treatment

Using organoids in precision medicine

Tumour-derived spheroids in culture

Patient-derived organoids can predict response

to chemotherapy in metastatic colorectal

cancer patients

Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials

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Clinical Applications

Clinical Applications