Organoid technology: will enable researchers to bridge the gap in our knowledge of development and disease processes
Tissue samples can be processed into cells or clumps of cells and grown in the laboratory so that they mimic the whole animal organ.
The cells grow in a self-organising 3D structure (an organoid) that is more like real tissue than cells grown on a flat on a plastic surface.
Organoids can be grown from normal or diseased tissue that can be collected from patient biopsies. This enables unprecedented study of both normal and disease processes and can even be used to predict patient response to drugs. These studies include organoids made from cystic fibrosis patients and cancer tissue.