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A Stem Cell is defined as a cell capable of giving rise to other cell types. Pluripotent cells can give rise to any cell type; restricted adult stem cells can produce cells in the tissue from which they are derived. 

Organoids can be grown from the two main types of stem cells:

(1) pluripotent embryonic stem (ES) cells which can be induced to produce any tissue

(2) organ-restricted adult stem cells

 

Both cell types exploit the seemingly infinite expansion potential of normal stem cells in culture.

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